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Translating science: Genomics and health systems

This project investigates the broad question: How is genomics knowledge translated in health systems and what are the consequent policy implications? Processes of translation involve the production of scientific knowledge, the protection of such knowledge through forms of intellectual property, and the interpretation, application, and commercialization of such knowledge. From a previous project founded in

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North American conditional mouse mutagenesis project: high throughput mammalian functional analysis for the discovery of novel determinants of human disease

The International Knock-out Mouse Project is a worldwide effort to generate knock-out mutations in every gene in the mouse genome – and is widely considered to be the next most important step following the Human Genome Project. This project aims to identify and characterize the functions of mouse genes to better understand the role of

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Building the metabolomic toolbox – enabling rapid disease diagnosis through metabolic profiling

This proposal aims to build on a number of unique Canadian research strengths and technologies in metabolic profiling to create: 1) comprehensive metabolite databases, and 2) new software and/or analytical tools to facilitate the rapid and inexpensive profiling of metabolites for disease diagnosis and management. Specifically, using a combination of analytical methods that includes mass

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Development and implementation of rapid metagenomic sequencing coupled with isothermal amplification point of care testing for viral diagnostics

Pandemic viral threats recur periodically as infectious agents recombine and disseminate in populations. In these instances, rapid identification of viral genome sequences is required in order to develop a targeted diagnostic test. This group has developed an approach called Metagenomic sequencing with spiked primer enrichment (MSSPE) which allows for highly sensitive detection of viral genomes

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Development and deployment of a computational tool for efficient whole-genome sequence association and prediction analyses

The goal of this project is to develop a powerful and efficient computing algorithm for whole-genome sequence association and prediction analyses. This project will provide the Alberta beef industry and research institutions with a powerful tool for fast integration of sequence information into genomic research and applications. Specifically, the newly developed algorithm and platform are

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BeeBiome Data Portal

The recent advent of sequencing technologies has enabled the generation of a large amount of bee microbiome data from different sources. There is an urgent need for those bee microbiome datasets to be made more accessible so that information can be applied for scientific discoveries and can be translated for stakeholder use. The goal of

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From sequencer to results: enabling routine genomics use for clinical and public health microbiology in Alberta

The goal of this project is to generate a portable and flexible platform that generates results from routine bioinformatics workflows, and adds the output to an accessible, database which can be integrated with additional data as needed. This goal will be achieved by the following three objectives: (1) develop a flexible database architecture to manage

From sequencer to results: enabling routine genomics use for clinical and public health microbiology in Alberta Read More »

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