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Development and deployment of MBVs/gEPDs for feed efficiency and carcass traits that perform in commercial beef cattle

The Canadian beef industry contributes more than $20B annually to the national economy, yet is challenged to remain globally competitive, use resources efficiently, and address human health concerns, climate change and environmental sustainability. This project will drive the adoption of genomic tools in the Canadian beef industry by generating more accurate breeding values in order […]

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Program on research and innovation leading to rapid detection of pathogenic E.coli: Rapid sampling and detection of STEC in meat

Pathogen contamination in meat has a very significant economic impact on the meat industry and a serious health impact for the public. Current testing protocols involve culture of material from meat products with serological or molecular confirmation. Since there continues to be recalls of beef after the product has been moved to the retail or

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Program on research and innovation leading to rapid detection of pathogenic E. coli: Point-of-need gene-based system for detection of priority STEC in beef

The consumption of food infected with diseases can lead to serious human health problems, violent gastrointestinal disease and potentially death, and to disastrous economic consequences to the agri-food industry due to food recalls. This project contains a research and development consortium composed of experts from academia, federal government agencies, food testing industry (PBR Laboratories Inc.),

Program on research and innovation leading to rapid detection of pathogenic E. coli: Point-of-need gene-based system for detection of priority STEC in beef Read More »

The integrated and distributed bioinformatics platform

The Integrated and Distributed Bioinformatics Platform (IBP) was formed in 2002 and was operational into 2011. The overall goal of the Platform is to provide a coherent and powerful bioinformatics infrastructure that can be used by all Genome Canada-funded laboratories (and other laboratories in Canada). Through this strategy, IBP provides unique hardware or CPU cycles,

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Canadian triticale biorefinery initiative – genomics of the rye parent

Triticale, the only man-made crop, results from a recent hybrid between rye and wheat. Triticale is a high yield grain and biomass plant that has an excellent degree of adaptability to abiotic stress and resistance to numerous diseases plaguing other cereal crops in North America. The development of triticale as an industrial platform has been

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Mass spectrometry-based structural proteomics for drug development & design

Proteins play a key role in important biological processes, and as such, are key targets for newly developed drugs. The three-dimensional model of a protein can be analyzed to find promising sites for potential drug binding, but determining the structure of a single protein typically takes months or even years. In order to speed up

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Enabling technologies for embryonic stem cell functional genomics

Embryonic stem (ES) cells have the potential to transform our knowledge of human disease and development and give rise to new classes of therapeutic agents – from novel drugs to cell-based therapies. To ensure Canada is strategically positioned to take full advantage of mouse and human ES cell resources, this proposal seeks to identify several

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Crop adaptation genomics – use of genomic tools for crop improvement in temperate climate

A key to maintaining and improving Canada’s position as leaders in grain production lies in crop improvement, a field of research that increasingly uses genomic approaches to identify genetic factors involved in the climatic adaptation of particular crops. The project will focus on three economically important crops – wheat, barley, and rye. Drawing on extensive

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Arborea II – genomics for molecular breeding in softwood trees

Spruce trees are the most widely used species in Canada’s forest plantations thus understanding its genomics is critical to improving tree growth and yield as well as wood properties, at the molecular level. Arborea II will create an inventory of the natural variability and expression of thousands of spruce genes. By identifying specific genes associated

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