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Value generation through genomics

Genomics research is fundamental to all biosciences and plays a critical role in diversifying the economy and improving the well-being of Canadians. The research themes include the role of regulation, knowledge and intellectual property management, democratic engagement, and technology transfer. Key findings from this research could provide evidence for decision makers in government, industry, and

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Metagenomics for greener production and extraction of hydrocarbon energy

Our present society is dependent on hydrocarbon resources. Until technologies exist to deliver a high proportion of our energy from renewable sources, at a reasonable cost, we must ensure that we extract the existing hydrocarbon resources in the most environmentally friendly manner possible. This project will allow Canada to satisfy the growing gap between the

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Listeria detection and surveillance using next-generation genomics (LiDS-NG)

The goal of this proposal is to develop cost-effective and rapid methodologies that allow enhanced screening for specific Listeria monocytogenes (Lm) genomic sequences associated with increased virulence potential and/or the ability to survive in food processing environments in a manner that can be done by any trained laboratory personnel. Currently, there are no adequate existing

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Modeling and therapeutic targeting of the clinical and genetic diversity of glioblastoma

Glioblastoma (GBM) is a deadly brain cancer that has eluded major treatment advances. Previous research methodology of growing stem cells from the brain was pioneered by a lead on this project out of the University of Calgary and a recently established cell-based model system provided this project with the foundation for an innovative drug discovery

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Translating Mountain Pine Beetle genomics outputs into tools for forest protection and resiliency

During this current outbreak, mountain pine beetle (MPB) has killed pines across more than 15 million hectares in British Columbia and Alberta. MPB is poised to continue its relentless spread through the jack pine of Canada’s boreal forests. This team will investigate how MPB and pine genetic variation influences MPB spread – focusing on the

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Mountain pine beetle epidemic

The current mountain pine beetle (MPB) epidemic in British Columbia is the largest bark beetle outbreak in recorded history. Despite the epidemic dimensions of the current MPB outbreak, very little is known about the molecular mechanisms and the population genomics of the interacting bark beetles, fungi, and trees. The proposed project will deliver advanced knowledge

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Improving Brassica oil content

This project focuses on studying regulatory networks and molecular events in the developing embryo, endosperm, and seed coat affecting seed oil accumulation in canola and related crops. The outputs of the project will provide a better understanding of the overall metabolic events and their contributions to the process of oil accumulation. Since meal quality traits

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