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The role of genomics in fostering and supporting arctic biodiversity: Implications for wildlife management, policy, and Indigenous food security

Wildlife genome information is extremely valuable for environmental decision making, yet much remains unused for this purpose. This project draws together partners with expertise across disciplines, cultures and organizations, building upon team strengths in Arctic observation and monitoring, biology, conservation, cyber-cartography, data management, genomics, geography, Indigenous Knowledge, the legal and policy sciences, and resource management. […]

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Transcriptional and epigenetic events underpinning Navacim-Induced TR1 cell formation and expansion

More than 100 autoimmune diseases have complex immune responses to autoantigens. Nanoparticles coated with autoimmune-disease-relevant peptide-major histocompatibility complexes (Navacims) have the potential to halt and cure autoimmune disease by restoring immune tolerance without compromising normal immunity to infections and cancer. They are currently the only technology that can activate internal generation of disease-specific regulatory T

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Genomic testing of wastewater to promote public health and safeguard economic performance

The COVID-19 pandemic has demonstrated the urgent need for early warning surveillance systems that can provide information to public health authorities on emerging COVID-19 variants and other infectious diseases. Wastewater-based epidemiology (WBE) is a non-invasive, comprehensive, and cost-effective early warning system that enables population-level monitoring independent of clinical testing. The research team has already developed

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TIGeR: Translational implementation of genomics for rare diseases

Alberta patients with or suspected of having rare genetic diseases continue to face lengthy diagnostic odysseys, and clinical genome wide sequencing has emerged as a rapid and cost-effective approach to diagnosis. Large scale clinical genomics are not available in Alberta, and Alberta Precision Laboratories (APL) has relied primarily on US commercial labs to provide clinical

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Summer Internship for Indigenous Peoples in Genomics (SING)

Low Indigenous representation across the genome sciences, ethics, and science policy fields is an ongoing problem. For one full week each summer, a University of Alberta developed initiative called Summer internship for Indigenous peoples in Genomics (SING) Canada, attacks these problems head on and via diverse themes. The annual SING summer program is all-expenses-paid, including

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The Metabolomics Innovation Centre (TMIC)

The Metabolomics Innovation Centre (TMIC) is Canada’s national metabolomics** laboratory, mandated to provide Canadian companies, scientists and trainees with access to comprehensive, cutting-edge metabolomic services and technologies. Originally launched in 2011 as a Genome Canada Science and Technology Innovation Centre, TMIC has received multiple renewed mandates to continue to grow and advance metabolomics as a

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The Canadian BioGenome Project

The richness of Canada’s biodiversity is under threat today due to climate change, habitat destruction and novel emerging diseases. A common thread across conservation strategies is the need for genomic tools to address knowledge gaps related to species evolution, adaption, viability, and genetic diversity. A reference-quality whole genome sequence is the foundation for such genetic

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Application of genomics to enhance wetland treatment systems for remediation of processed water in northern environments

Constructed wetland treatment systems (CWTS) are one of very few scalable and cost-effective technologies for remediating large volumes of wastewaters. An in-depth understanding of how these nature-based, passive, low energy systems operate to treat industrial waste is needed to enhance treatment efficacy in cold weather, particularly in northern environments that are challenged by short summers

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TRIA-FoR: Transformative risk assessment and forest resilience using genomic tools for the Mountain Pine Beetle outbreak

Over the past two decades, mountain pine beetle (MPB) has killed more than 20 M hectares of mainly lodgepole pine forests in western Canada. In the wake of this MPB epidemic, decision makers seek reforestation strategies that increase forest resiliency to future outbreaks. Simultaneously, the uncertain risk that MPB poses to jack pine challenges decision

TRIA-FoR: Transformative risk assessment and forest resilience using genomic tools for the Mountain Pine Beetle outbreak Read More »

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