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Development and testing of an at-home lung cancer-screening test

This project aims to address the urgent need for the early detection of lung cancer (LC). Nearly 50% of Canadian LC cases are diagnosed at Stage IV, leading to very low survival rates. This project focuses on two key objectives: 1) developing and validating a blood plasma-based, laboratory-developed test (LDT) for early-stage LC detection and […]

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“Mainstreaming” Genetic Testing for Non-Ischemic Cardiomyopathy in Western Canada: A Family-Centred and Genome-First Approach to a Common and Life-Threatening Cardiomyopathy

Heart muscle disorders are a common cause of heart failure: a life-threatening condition that can cause dangerous abnormal heart rhythms (arrhythmia) and a buildup of fluid in the body (edema). In British Columbia (BC) and Alberta, patients with heart failure are cared for in specialized Heart Function Clinics (HFC). Providers in these clinics rapidly diagnose

“Mainstreaming” Genetic Testing for Non-Ischemic Cardiomyopathy in Western Canada: A Family-Centred and Genome-First Approach to a Common and Life-Threatening Cardiomyopathy Read More »

Expanding the Use of Genomics to Unravel Rare Diseases: Care4Rare EXPAND

This sequencing project will help accelerate rare-disease diagnosis and discovery with the goal of ending the costly and burdensome diagnostic odyssey for thousands of Canadian families. Care4Rare EXPAND is a four-year collaborative research project to build a rare disease (RD) dataset. We will generate a diverse genomic asset of 17,650 datasets from 7,150 families with

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Genomics of Stroke and Cerebrovascular Disease

This sequencing project will develop new, more effective stroke prevention, risk assessment and precision diagnostic strategies for Canadians. More than 62,000 Canadians have a stroke each year. Stroke is the fifth leading cause of death and a leading cause of disability. Survivors often face long-term challenges such as physical disabilities, cognitive impairments and emotional distress.

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Longitudinal, Deep-Phenotyped Pediatric Databank of Medical and Drug Therapy Outcomes

This sequencing project will enable improvements to drug safety and effectiveness in children by making genomic data on their responses and adverse reactions to various medications more widely accessible to researchers and health regulatory agencies. This project will leverage the existing resources of the Canadian Pharmacogenomics Network for Drug Safety (CPNDS) to bring a pediatric

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Pan-Canadian Initiative Linking Genomic, Environmental and Mental Health Data in Children and Youth (Pan-GEM)

This sequencing project will identify interacting genetic and environmental risk factors for children and youth with mental health disorders, supporting earlier intervention. Mental health disorders (MHDs) typically begin early in life (75 per cent before the age of 25) affecting an estimated one in five children and youth (1.6 million Canadians). MHDs are highly heritable,

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GlycoNet Integrated Services

Glycomics is poised to be the major contributor to two of the fastest-growing industry sectors globally (biotechnology and pharma), building on the already transformative impacts of genomics and proteomics. GlycoNet Integrated Services (GIS) was launched with the vision of becoming the world’s leading glycomics service provider. GIS’ glycomics toolbox uniquely equips glycomics researchers, partners and

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PeaCE (Pea Climate-Efficient): Developing climate-resilient, low carbon footprint field pea as a preferred rotation crop through the inter-disciplinary integration of genomic technologies

The global demand for food is expected to increase by 35–50% by 2050. To meet this demand and alleviate strain on agriculture, synthetic nitrogen fertilizers are increasingly applied to oilseeds and cereal crops to maximize yields. However, nitrogen fertilizer contributes to nitrous oxide emissions, a powerful greenhouse gas (GHG) that is approximately 300 times more

PeaCE (Pea Climate-Efficient): Developing climate-resilient, low carbon footprint field pea as a preferred rotation crop through the inter-disciplinary integration of genomic technologies Read More »

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