Health

Non-invasive prenatal screening (NIPS) genomics analysis of cell free DNA in maternal blood has the potential to perform well as a first-tier screening test for aneuploidies. NIPS use as a first-tier screening test would simplify, streamline, and enhance the safety of prenatal screening for fetal aneuploidies and could potentially detect other important fetal abnormalities. However, […]

There are about 7,000 rare genetic diseases (RDs) that affect more than one million Canadians. RDs have a devastating impact on Canadians: two-thirds cause significant disability, three-quarters affect children, more than half lead to early death, and almost all have no treatment. The cause of more than one-third of the 7000 RDs is currently unknown.

The global rise in the prevalence of antibiotic resistant bacteria is a serious problem, threatening all modern medicine. A primary reason is the one-size-fits-all approach to treating infections, which encourages overuse of drugs and results in unnecessary sickness and death. To address this problem, this project is using metabolomics to create an automated analytical system

The mission of the Canadian COVID-19 Genomics Network (CanCOGeN) is to establish a coordinated pan-Canadian, cross-agency network for large-scale SARS-CoV-2 and human host sequencing to track viral origin, spread and evolution, characterize the role of human genetics in COVID-19 disease and to inform time-sensitive critical decision making relevant to health authorities across Canada during the

Living with cancer longer is possible due to better cancer treatments but these treatments can damage the cardiovascular system. This can happen in up to 15-20% of people receiving treatment for breast and other aggressive cancers. The purpose of this project is to develop a state-of-the-art database system, called the CArdiotoxicity Prevention Research Investigation (CAPRI).

Precision Health is an emerging paradigm that promises to improve the health of Albertans by considering each patient’s unique genomic, environmental and lifestyle characteristics to create personalized prevention and treatment plans. To realize the full potential of precision health, newer methods of integrating high quality clinical information with genomic data and methods to improve sharing

Unchecked inflammation underlies complex immune-mediated conditions, including arthritis, resulting in significant morbidity and high costs. This project aims to overcome the barriers to integrate precision health data and accelerate its translation and application into practice in the context of inflammatory arthritis. Precision Health requires standardized data collection and integration including clinical, environmental, biologic, and administrative

Precision health represents a spectrum of transformative approaches from medicine to public health. Precision medicine aims to harness a wave of discoveries in genomics to deliver the right treatment to the right patient at the right time. Precision public health aims to apply those discoveries to better direct public health interventions. The Alberta Laboratory for

The GAPH Network brings together GE3LS (the Genomics and its ethical, environmental, economic, legal, and social aspects) components of the 17 projects funded through Genome Canada’s Genomics and Personalized Health programme (GAPH), with the objectives of: sharing best practices, improving and priming future collaborative research endeavours, accelerating the progress to market of GAPH technologies, and