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ActiveAgriculture & Agri-food

An “omics” approach to characterization of the microactome and identification of new therapeutic targets for the prevention of liver abscesses and bovine respiratory disease in feedlot cattle

PROJECT LEAD(S)/CO-LEAD(S) Tim McAllister (Agriculture and Agri-Food Canada (AAFC) Lethbridge Research and Development Centre) & Leluo Guan (University of Alberta)
FUNDER Genome Alberta/Results Driven Agriculture Research
PROJECT START DATE January 1, 2020
PROJECT END DATE December 31, 2023
COMPETITION/ FUNDING OPPORTUNITY Genome Alberta/Results Driven Agriculture Research
ALBERTA’S ROLE Lead

BUDGET

$1,200,000

Liver abscesses and bovine respiratory disease (BRD) cause the greatest disease associated economic losses in the Canadian Beef Industry. As these conditions are mainly caused by Gram-negative bacteria, this combined with antimicrobial resistance (AMR) may account for the limited efficacy of current antimicrobials. This project will use “omic” technologies to characterize the interaction between these disease-causing microbiomes and the host in a relationship defined as the “microactome”. This project represents one pillar in a large AAFC project entitled Mitigating the development.

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