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ClosedAgriculture & Agri-food

A comprehensive analytical toolkit and high‐performance genome browser for rapid, reliable, and in‐depth characterization of bacterial genomes

PROJECT LEAD(S)/CO-LEAD(S) Paul Stothard (University of Alberta) & Gary Van Domselaar (Public Health Agency of Canada)
FUNDER Genome Canada - 2017 Bioinformatics and Computational Biology Competition
PROJECT START DATE October 1, 2018
PROJECT END DATE September 30, 2022
COMPETITION/ FUNDING OPPORTUNITY Genome Canada - 2017 Bioinformatics and Computational Biology Competition
ALBERTA’S ROLE Lead

Genomes represent the ‘recipe’ of life for all living organisms, providing instructions for how they are built, the environments in which they are designed to live, and the things that they can do in those environments. Genome sequencing instruments can now sequence an organism’s genome; however, the results do not come out in one piece, instead, sequences are generated in many short pieces, likened to the words from the book. The goal of this project is to provide a suite of analytical tools that can accurately put together the jumbled collection of sequence fragments coming out of current genome sequencing instruments, to identify the genes and other embedded “instructions”, and then to illustrate them in ways that are familiar to researchers, and in ways that are useful for conveying important genomic information that may provide new insights. Applying the team’s sophisticated yet user‐friendly computer platform to decode the ‘recipes’ in bacterial genomes and to translate these insights into new discoveries, products, and processes will contribute to Canada’s economy and the sustainability of its biological resources for many years to come.

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